UGTLDUGT LAB FOR DISCOVERY

Starting from a metabolite,find UGTs worth validating.

Which plant UGTs are worth validating for a target metabolite?

Connecting plant UGT resources, structural assessment, AI-supported prioritization and multi-omics evidence to identify candidates for experimental validation.

Explore the platformRead the researcher guide

The public site explains methods. Authorized projects and research data stay in the Research Workspace.

Published PDB reference structureThe reference image is not available. The research workflow and source link remain usable.
Vitis vinifera flavonoid UGTPublished reference · PDB 2C1Z
RCSB PDB 2C1ZPublication DOI
Published reference structure · Not a UGTLD project result

Five research stages, one traceable path.

Start with a molecule. Narrow the UGT candidate space through distinct evidence, then decide what merits experimental validation.

See how the workflow works
01

Target metabolite

Define the acceptor, plant context and reaction question. A chemical identity belongs to the study input, not to an illustration.

Plant and substrate contextMethod schematic · no compound identity or study result is shown.
Method schematic · botanical context and substrate input
02

UGT resources

Resolve species, sequence identity, family, PSPG motif and phylogenetic context before candidate interpretation.

UGT resource relationshipsMethod schematic · not a phylogeny or sequence result.
Method schematic · resource relationships, not a tree result
03

Structure & AI assessment

Inspect structures, donor-aware docking and model outputs in context. A completed prediction supports a hypothesis; it does not establish activity.

Methods and structural limits
Published flavonoid UGT referencePDB 2C1Z · KMP and U2F bound · not a UGTLD result.
Published reference crop · PDB 2C1Z · bound ligands shown in gold · not a UGTLD project result
04

Biological evidence

Interpret expression and omics with tissue, sample, treatment and identifier context. Missing measurements remain missing.

Dataset-to-evidence pathMethod schematic · no sample-backed values are shown.
Method schematic · dataset, sample context and evidence record
05

Candidate prioritization

Compare evidence source, availability, coverage, priority and researcher decision as separate fields. No single unexplained score replaces that review.

Candidate comparison structureMethod schematic · no candidates, ranks or scores are shown.
Method schematic · no candidate identities or rankings

Three workspaces, three different scopes.

Public explanation, account-wide resource management and project-specific analysis are separate parts of the product.

Product architecture
  1. Open reading

    Public Website

    Review platform methods, public resources, cases, documentation and product boundaries.

    Platform and methods
  2. Across projects

    Research Workspace

    Manage projects, species, UGT, metabolite and omics resources, personal data, results and exports under the signed-in account.

    Authorized workspace access
  3. One project

    Project Workspace

    Keep one study's context across candidate discovery, evidence analysis, integrated assessment, mechanism research and research outputs.

    Researcher guide

Each method answers a different question.

Inputs and outputs stay traceable; evidence availability is not the same as evidence strength.

Explore platform methods
Research viewInputsMethodReviewable output
UGT family contextSpecies, sequence records, identifiersFamily and motif annotation; phylogenetic placement where availableCandidate identity, source and evolutionary context
Structure & AISequence, structure, acceptor and donorStructure assessment, Boltz-2 and donor-aware sequential docking when configuredModel artifacts, pose and geometry evidence, method limits
Biology & omicsDataset, expression matrix, sample metadata and identifier mapTissue, condition and pathway contextMapped evidence with missingness and provenance retained
Candidate comparisonCandidates and available evidence recordsCompare evidence axes, coverage, priority and researcher decision separatelyTraceable comparison, report and research package

Published references and method examples.

Public figures explain the evidence pathway. They do not imply a UGTLD project result.

View cases and evidence boundaries

Flavonoid UGT structure

Published reference

PDB 2C1Z is a published Vitis vinifera flavonoid 3-O-glucosyltransferase structure with bound ligands. It provides structural context; it is not a UGTLD project result.

Open the source record

Family and omics schematics

Method schematic
Family relationship viewNo taxon or phylogeny result is shown.
Resource and family relationships · no tree result
Expression review contextNo sample values or expression results are shown.
Tissue and sample context · no expression values

No public UGTLD candidate case is configured. Candidate-level project results require authorization and publication approval; this page contains no project ranking or experimental activity claims.

Bring a research question. Keep the evidence reviewable.

Use the guide to understand inputs and limits. Authorized research data and project analysis remain inside the Research Workspace.

Read the researcher guideWorkspace access